# HotHouse Therapeutics ## Posts - [HotHouse Therapeutics is featured in C&EN, the leading authority in global chemistry news by the American Chemical Society](https://hothousetx.com/hothouse-therapeutics-featured-in-cen/): We were delighted to be interviewed by Max Barnhart of C&EN about our coming-out-of-stealth story. “The company says its AI and synthetic biology platform can produce compounds not possible with traditional synthesis. HotHouse Therapeutics has emerged from stealth with a little over $3 million in preseed funding. The start-up, based in Norwich, England, mixes artificial intelligence and synthetic biology to reprogram plant biosynthetic pathways to create new molecules.” Read the article in full here: HotHouse launches to remix plant compound biosynthesis for pharma - [HotHouse Therapeutics Emerges from Stealth with £2.9m Funding to Revolutionise Modern Medicine](https://hothousetx.com/hothouse-therapeutics-raises-2-9m-in-funding/): Pioneering drug discovery platform company, HotHouse Therapeutics has successfully closed a £2.9m pre-seed funding round to transform modern medicine by developing sustainable, scalable pharmaceutical compounds through AI-optimised plant-based chemistry. The investment – from SynBioVen, Start Codon, UKI2S, Twin Path Ventures, Wren Capital, a number of angel investors and an Innovate UK grant – comes as the Norwich-based startup emerges from stealth mode, where the team has been deploying its platform to solve one of the vaccine industry’s most pressing problems: the global dependence on a single, unsustainable source of the critical adjuvant, QS-21. Today, QS-21 is sourced from the bark […] - [Celebrating Professor Anne Osbourn’s Global Recognition](https://hothousetx.com/anneosbourneclarivate/): We are proud to share that Professor Anne Osbourn has been named on the Clarivate Highly Cited Researchers 2025 list, recognising researchers whose work is ranked among the top 1% by citations in their field over the past decade. This acknowledgement reflects the deep impact of her research and the strength of the science that underpins our company. Anne’s work at the John Innes Centre uncovered that the biosynthetic pathways for complex plant natural products are organised in gene clusters within plant genomes. That discovery laid the scientific foundation for what we do today. At HotHouse Therapeutics we build on […] - [HotHouse Therapeutics Attends WVC Europe 2025](https://hothousetx.com/wvceu/): This week, HotHouse Therapeutics joined the World Vaccine Congress Europe 2025 in Amsterdam, bringing our mission front and centre into the heart of the vaccine community. The event, held October 13-16 at RAI Amsterdam, covered the full vaccine value chain – from early R&D to large-scale manufacturing. Key Themes from WVC Europe 2025 Several discussions this week echoed HotHouse Therapeutics’ mission to make vaccine innovation faster, smarter, and more sustainable. These themes highlight a shared belief that the future of vaccines relies on more innovative technology and greener production methods. Our reflections & focus For HotHouse Therapeutics CEO David Sheppard, […] - [HotHouse Therapeutics nominated for #21toWatch Awards](https://hothousetx.com/21towatch-awards/): We’re proud to be nominated in the ‘Company’ category of the #21toWatch Awards 2026, which celebrate the innovators and businesses shaping the future of Cambridge and the East of England. Our nomination reflects our pioneering AI-driven, carbon-positive drug discovery and plant-based engineering platform – a plug-and-play system currently being deployed into adjuvants and transforming vaccine development. By combining advanced AI with plant bioengineering, we’re creating novel molecules and hard-to-source adjuvants, delivering next-generation therapeutics sustainably and at scale. Our environmentally responsible production model ensures a long-term, resilient supply of complex compounds – without depleting natural resources or harming ecosystems. “HotHouse Therapeutics has been in stealth mode […] - [Professor Anne Osbourn has been elected to EurAsc](https://hothousetx.com/eurasc/): We are delighted to announce that HotHouse Therapeutics’ co-founder, Prof. Anne Osbourn, has been elected to the Medicine and Life Sciences Division of the European Academy of Sciences (EurASc). Read more here: https://www.eurasc.eu/members/anne-osbourn/member/ - [From Chilean trees to global health: why vaccine supply needs to change](https://hothousetx.com/observersept25/): Professor Anne Osbourn is bringing global attention to the fragile supply of one of the world’s most important vaccine ingredients. HotHouse Therapeutics’ co-founder and Chief Scientific Officer, Professor Anne Osbourn, is helping shine a spotlight on a pressing global challenge: how we source vaccine ingredients. The Chilean soap bark tree produces QS-21, a potent adjuvant found in vaccines for malaria, shingles and COVID-19. But supplies rely on bark stripped from trees that take decades to mature, raising questions about sustainability and resilience in the face of rising demand. Anne’s research highlights not only the promise of QS-21 but also the […] - [HotHouse Therapeutics is coming to Cambridge Tech Week 2025!](https://hothousetx.com/hothouse-therapeutics-is-coming-to-cambridge-tech-week-2025/): We will be at Cambridge Tech Week on Tuesday 16th Sept - please come and find us at the Cambridge Management Consulting stand! - [HotHouse Therapeutics pitches at KPMG’s Tech Innovator UK Regional Final](https://hothousetx.com/hothouse-therapeutics-pitches-at-kpmgs-tech-innovator-uk-regional-final/): We are delighted to be amongst the finalists at the East of England Tech Innovator UK awards. - [HotHouse Therapeutics to present at London Tech Week 2025](https://hothousetx.com/hothouse-therapeutics-to-present-at-london-tech-week-2025/): London Tech Week provides an excellent opportunity to showcase what we are developing at HotHouse Therapeutics to a brilliant tech audience. - [HotHouse Therapeutics exhibits at The World Vaccine Congress USA](https://hothousetx.com/hothouse-therapeutics-exhibits-at-the-world-vaccine-congress-usa/): The HotHouse Therapeutics team will showcase our exciting work in next generation adjuvants. - [HotHouse Therapeutics Joins the NVIDIA Inception Program](https://hothousetx.com/nvidianov24/): We’re excited to share that HotHouse Therapeutics has joined the NVIDIA Inception program – a global initiative that helps startups scale with access to cutting-edge technology, expertise, and support. For us, this is an opportunity to supercharge our BotanAI and BotanBIO platforms, where AI meets nature to grow novel, sustainable medicines. With the resources and guidance from the NVIDIA Inception program, we’ll be able to design and optimise molecules faster, opening up new possibilities for vaccines and therapeutics. The NVIDIA Inception program helps us move faster toward our mission: growing greener medicines that are smarter, scalable, and ready for global impact. - [HotHouse Therapeutics featured by NRP](https://hothousetx.com/hothouse-therapeutics-featured-by-nrp/): Hot House Therapeutics was delighted to be featured in an article released by Norwich Research Park. Click more to find the link to the article. - [Prof Osbourn receives Novozymes Prize](https://hothousetx.com/prof-osbourn-receives-novozymes-prize/): Plant scientist Anne Osbourn receives prestigious Novozymes Prize for her pioneering work of producing important drugs in greater volumes and improving the natural defence systems of plants. ## Pages - [Our Team](https://hothousetx.com/team/) - [News & Insights](https://hothousetx.com/news/): The latest news about HotHouse Therapeutics - [Privacy & Cookies](https://hothousetx.com/privacy-policy/): This policy explains when and why we collect personal information about people who visit our website. By using our website, you’re agreeing to be bound by this policy. When someone visits this website, we use Google Analytics, to collect standard internet log information and details of visitor behaviour patterns. This information is processed in a way that does not identify anyone and we do not make any attempt to find out the identities of those visiting our website. If you complete a form to sign up for our newsletter or otherwise send us an email, this information will be stored […] - [Homepage](https://hothousetx.com/) [comment]: # (Generated by Hostinger Tools Plugin)